Evaluation of oxidative stress in pregnants with chronic hepatitis B and C

Aim: This study was aimed to investigate the levels of antioxidant markers (paraoxonase, superoxide dismutase, glutathione peroxidase, and thiol) oxidative stress (advanced oxidation protein products, xanthin oxidase, nitric oxide, malondialdehyde, 8-hydroxydeoxyguanosine) in pregnant women with chronic hepatitis B C. Material Method: Sixty last trimester, 20 whom had B, another C, remaining were healthy controls, enrolled this study. Demographic, clinical laboratory data recorded for all patients. Results: When compared C displayed significantly lower paraoxonase, thiol (p<0.001). Superoxide dismutase also patients, comparison yet difference statistically insignificant (p=0.76). Compared patients higher advanced xanthine oxidase The oxide than those control group (p<0.05). No significant observed between controls malondialdehyde 8-hydroxydeoxyguanosine (p>0.05). Conclusion: Oxidative increased chronically infected viruses, when women. Thus, we suggest that viruses should be closely monitored throughout pregnancy diseases induced by oxidant-antioxidant imbalance, such as preeclampsia, gestational diabetes hypertension.